Immunological function in the aspect of killer cells.
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概要
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The immunological functions of 60 patients with head and neck cancers and 27 patients with gastrointestinal cancer were evaluated using in vitro natural killer cell (NK) activity, lymphokine activated killer cells (LAK) and OK-432 activated killer cells, as well as by in vivo PPD and Su-PS skin tests. There were significant differences of the above three activities between stage I cancer patients and stage III and/or IV (p<0.05). The PPD skin test corresponded significantly to LAK activity, while Su-PS corresponded significantly to OK-432 activated killer cell activity (r=0.5558; p<0.05, and r=0.4753; p<0.01, respectively). Responses to interleukin-2 and OK-432 of stage IV patients with head and neck cancers were different from those of stage IV with gastrointestinal cancer. These in vitro assays were very useful for the evaluation of immunological function in head and neck cancer patients, especially before any treatments with biologocal response modifiers.
- 日本頭頸部癌学会の論文
日本頭頸部癌学会 | 論文
- 口腔白板症に対する緑茶カテキンの治療効果に関する臨床的検討
- SUPERSELECTIVE ARTERIAL INFUSION AND CONCOMITANT RADIOTHERAPY FOR ADVANCED HEAD AND NECK CANCER
- MICROVASCULAR SURGERY IN HEAD AND NECK SURGERY
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