Metabolic Syndrome and Insulin Resistance in Japanese Males-Tanno-Soubestu Study
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概要
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According to the American NCEP-ATP III (National Cholesterol Education Program-Adult Treatment Panel III) criteria, metabolic syndrome is characterized by an abnormal abdominal circumference (AO), high blood pressure (HT), high fasting glucose (HFPG), high triglyceride level (HTG) and low HDL cholesterol level (LHDL). The present study investigated the concept of metabolic syndome with regand to insulin resistance in Japanese males. The subjects consisted of 808 males (60±12years) living in two rural communities in Hokkaido, Japan, who had undergone health screening examinations and a 75g oral glucose tolerance test. The subjects were divided into a metabolic syndrome (MS) group (24.4%) and a non-MS group (75.6%) based on the NCEP-ATP III criteria (but with the criterion for AO being 85cm). The overall percentages of patients with an AO, HTG, LHDL, HT and HFPG were each 42.7%, 34.1%, 16.7%, 59.1% and 13.5%, respectively. As the number of risk factors increased from 0 to 5, the level of 120-IRI, HOMAR increased significantly. A multiple regression analysis showed that 120-IRI and HOMA-R were significantrisk factors in a model that included BMI and age. The presence of metabolic syndrome may be useful for predicting insulin resistance in Japanese males.
- 一般社団法人 日本糖尿病学会の論文
一般社団法人 日本糖尿病学会 | 論文
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