Report of the Committee on Standardization of Laboratory Testing Related to Diabetes Mellitus: Usefulness of Venous Blood Method As a Standardized Comparative Method for Blood Glucose Measurement Using Devices for Self-monitoring Blood Glucose.:Usefulness

概要

論文の詳細を見る
The Japan Diabetes Society (JDS) Committee on Standardization of Laboratory Testing Related to Diabetes Mellitus surveyed in 1999 the device-to-device variation in blood glucose measurement among 6 selfmonitoring blood glucose (SMBG) devices, and reported significant deviation. The committee suggested that the device-to-device variation was due to the difference in manufacturers'own comparative method and proposed to SMBG manufacturers the venous blood method as a standardized comparative method. Venous blood samples with various glucose levels were made from heparinized venous blood, drawn from healthy subjects, either incubated at 37°C for 4 hours or not, and then were mixed with salined glucose solution added at different concentrations. Blood glucose in these blood samples was then measured with SMBG devices adjusted to the levels of glucose determined with conventional hexokinase method. Results for 10 SMBG devices confirmed the usefulness of venous blood as a standardized comparative method. In the 10 SMBG devices tested, the bias, difference in and mean glucose'levels between hexokinase and SMBG devices were scattered almost in a range of±15 mg/d<I>l</I>, and Sy/x, standard errors of regression equations, were less than 10 mg/d<I>l</I>.
一般社団法人日本糖尿病学会の論文