A Diabetic Patient whose Fasting Hyperglycemia was Extremely Improved by Domperidone. Discussion of Continuously Monitored Plasma Glucose Levels and Changes in Counter-Regulatory Hormones.:Discussion of Continuously Monitored Plasma Glucose Levels and Cha
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We experienced a 73-year-old female patient with diabetes mellitus of 9 years or more duration who had high fasting plasma glucose levels because of a possible rebound phenomenon after delayed gastric emptying.<BR>We measured her plasma glucose levels overnight by continuous monitoring and found hypoglycemia followed by fasting hyperglycemia.Domperidone, 10 mg, was then administered to the patient at 9: 00 pm, and this was followed by marked improvement of the patient's high fasting plasma glucose levels. Before treatment with domperidone, the patient's growth hormone level at 3: 00 am and glucagon, adrenocorticotropic hormone and cortisol levels at 6: 00 am had been high. All of them decreased to within the normal range after the high fasting plasma glucose levels had been improved by treatment with domperidone.These counter-regulatory hormones appeared to have augmented the fasting plasma glucose levels.The above results suggest that it is important to try domperidone in patients suffering from rebound high fasting plasma glucose as a result of gastroparesis.
- 一般社団法人 日本糖尿病学会の論文
一般社団法人 日本糖尿病学会 | 論文
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