Enteropathogenic Escherichia coli Strains Harboring Enteroaggregative Escherichia coli(EAggEC) Heat-stable Enterotoxin-1 Gene Isolated from a Food-borne Like Outbreak.:Gene Isolated from a Food-borne Like Outbreak
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概要
- 論文の詳細を見る
A food-poisoning outbreak occurred in G Town in Minami-Akita District, Akita Prefecture on 16 January 1995. As the causative agent of the outbreak, Enteropathogenic <I>Escherichia coli</I> (EPEC) O126: NM were isolated. The isolates showed the same plasmid profile and antibiotic susceptibility patterns suggesting that the EPEC strains originated from same infectious source.<BR>The isolates lacked <I>eae</I> and EAF genes which were considered to play a significant role in the diarrheagenic mechanism of EPEC. On the otherhand, the isolates possessed Enteroaggregative E. <I>coli </I> (EAggEC) heat-stable enterotoxin-1 (EAST-1) gene, though they did not possess the <I>agg </I>A gene in which the coded structural subunit of Aggregative adherence fimbriae 1 (AAF/ 1) has been demonstrated to be involved in the expression of ability for EAggEC to adhere to cultured cells in aggregative pattern, indicating that the EPEC strains apparently differed from EAggEC.<BR>These data suggested that EAST-1 showed its enterotoxic activity to human, and that EPEC represented multiple category of E. <I>coli</I> strains with different diarrheagenic mechanism, in which both <I>eae</I> and EAST-1 might be involved.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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