Efficasy of erythromycin(EM) for extubation of tracheostomy tube in 4 cases of chronic respiratory disease.
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概要
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Weaning of patients supported by prolonged artificial ventilation is difficult on account of complicated incurable lower air way infections by <I>P. aeruginosa</I> etc. Four typical cases of lower air way infections responded positively to EM.<BR>(Case 1) A 70 years old male patient had both upper lung lobes resected in the past due to T. B. Since the onset of respiratory failure when he underwent a surgical operation due to gastric cancer, he inevitably needed continual support by artifical ventilation and this was complicated by a lower air way infection by <I>P. maltophilia</I>. Application of EM brought about a successful weaning and he was able to be discharged.<BR>(Case 2) A 74 years old female patient was inevitably supported by a continuous artificial ventilation due to sever attacks of bronchial asthma which gave rise to a complicated lower air way infection by <I>P. aeruginosa</I>. Application of EM resulted in anacceptable healing, and she was discharged.<BR>(Case 3) A 56 years old male patient, with previous artificial pneumothorax due to T. B., needed the support of a contunous artificial ventilation upon the occurrence of an acute exacerbation, which gave rise to a complicated lower air way infection by <I>P. aeruginosa</I>. Application of EM resulted in healing and then he was able to be discharged.<BR>(Case 4) A 50 years old male, who was prescribed predonisolone due to sarcoidosis, gave rise to a complicated lower air way infection of <I>Aspergillus, M. tuberuculosa</I>, and <I>P. aeruginosa</I>. Consequently the respiratory failure was relieved by a tracheostomy. Many antibiotics and EM were then applied. Notwithstanding an inevitable interruption of anti-P. aeruginosa agents due to a fever, his clinical course was good so he could be discharge.<BR>These 4 cases suggestted the efficacy of EM for the treatment of lower air way infection of patients tracheomized with chronic respiratory diseases.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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