Studies on Serological Classification of Staphylococci
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概要
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Classification of staphylococci by phage typing has not been brought to widespread use mainly because of procedural complexity and relatively low typability. On the other hand, serological classification has been attempted by many workers, such as Heina (1922), Julianelle (1922), Yonemura (1936), Cowan (1939), Oeding (1952), and Akiyama (1959), who showed that pathogenic staphylococci could be subdivided by means of agglutination reactions. Serological method is less complicated in procedures than phage typing but not popularized yet. The reason seemed to be the lability in the structure of antigen. Akiyama found that the treatment of the bacteria with 2% NAOH completely inhibited the spontaneous agglutination. He used boiled bacteria for the production of immune sera, and for absorption and agglutination tests. Reexamining Akiyama's method, the authors found that using alkali-treated boiled bacteria sometimes causes some change in the structure of antigen in the course of successive subcultures.
- The Japanese Association for Infectious Diseasesの論文
The Japanese Association for Infectious Diseases | 論文
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