Therapeutic Effects and Adverse Reactions to D-Penicillamine
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概要
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The therapeutic effects of D-penicillamine were evaluated statistically in 44 patients with rheumatoid arthritis, and the adverse reactions were investigated in 47 patients including 3 patients with progressive systemic sclerosis.<BR>Statistically, significant improvement was observed especially in the number of painful joints, erythrocyte sedimentation rate and grip strength of hands. D-penicillamine, like gold salts, was proved to be undoubtedly an effective anti-rheumatoid drug. The adverse reactions were observed in 55.3% of the patients, including 4 patients in which major of fatal reactions were seen. Therefore, D-penicillamine should be used carefully and the therapy should be started with the lowest dose.
- 一般社団法人 日本医療薬学会の論文
一般社団法人 日本医療薬学会 | 論文
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