THE MAMAGEMENT OF ANTIPLATELET THERAPY FOR ENDOSCOPIC PROCEDURES:-THE OPTIMAL CESSATION PERIOD OF ANTIPLATELET THERAPY FOR JAPANESE-

概要

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Although antiplatelet agents are widely used for the treatment and prevention of thrombotic diseases, only a few studies have reported the validity of the cessation period prior to endoscopic procedures. There is a reference of the guideline on the management of anticoagulation and antiplatelet therapy for endoscopic procedures by the American Society for Gastrointestinal Endoscopy (ASGE) in 2002, but it should be confirmed in appropriation for Asian people. To evaluated the optimal cessation period of antiplatelet agents prior to an endoscopic procedures for Japanese, we have studied 1) the current clinically adopted cessation period of antiplatelet agents prior to invasive endoscopic procedures in Japan, 2) the relationship between the cessation period of antiplatelet agents and complications around the invasive endoscopic procedures, 3) colonic mucosal bleeding time after aspirin ingestion and 4) the time course of primary hemostasis after cessation of antiplatelet agents. We conclude that 3 days of cessation period for aspirin, 5 days of cessation for ticlopidine and 7 days of cessation for aspirin+ ticlopidine administration should be sufficient for Japanese.
社団法人日本消化器内視鏡学会の論文