A CASE OF METACHRONOUS MULTIPLE PRIMARY CANCER OF THE GALLBLADDER CARCINOMA AND THE EARLY BILE DUCT CARCINOMA

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A 66-year-old woman, who had been performed extended cholecystectorny for advanced gallbladder carcinoma in pct.1983, was admitted to Iwakuni Medical Center Hospital with complaints of epigastralgia and vomiting on pct.1, 1994. The elevated lesion in, middle bile duct was pointed out by endoscopic retrograde cholangiogram(ERC)and, subsequently, she was referred to our hospital. Peroral cholangioscopy(POCS)proved the presence of papillary tumor with microgranular surface and its cytology discloscd class V. A bile duct carcinoma was diagnosed, because ARC demonstrated normal residual cystic duct and the tumor was demonstrated within the wall of the bile duct by U5, CT, MRI and EUS. Resected specimen revealed early bile duct carcinoma limited to the fibro-muscular layer without lymphnode metastasis. There is an interval of ll years between the first gallbllader carcinoma and the second bide duct carcinoma.This is the sixth case of metachronous multiple primary biliary cancer reported in Japan.
社団法人日本消化器内視鏡学会の論文