Antagonistic effect of yohimbine on xylazine-induced sedation, bradycardia and hypothermia in cats.
スポンサーリンク
概要
- 論文の詳細を見る
Antagonizing effects of yohimbine, α<SUB>2</SUB>-adrenoceptor blocking agent, at various doses on sedation, bradycardia and hypothermia induced by xylazine in cats were studied. Cats were given a standard dose (2mg/kg) or an overdose (5mg/kg) of xylazine, followed by i.m. or i.v. injections of various doses of yohimbine. Both i.m. (0.1-0.3 mg/kg) and i.v. (0.05-0.5mg/kg) injections of yohimbine markedly reduced the recovery time from xylazine-induced sedative effects. In addition, yohimbine reduced or abolished xylazine-induced Bradycardia and hypothermia. Those antagonizing effects of yohimbine seemed to be dosedependent. However, yohimbine given i.v. at a dose of more than 0.3 mg/kg appeared to cause restlessness or excitation. These results suggest that yohimbine can be used as a safe and effective antagonist against xylazine at doses of 0.05 to 0.1 mg/kg i.v. or 0.1 to 0.3 mg/kg i.m..
- 獣医麻酔外科学会の論文
獣医麻酔外科学会 | 論文
- 犬の麻酔侵襲における末梢血リンパ球アポトーシスの変動
- 猫の大腿骨骨幹部粉砕骨折に対してV字型髄内ピンとワイヤーを応用した整復法
- パンチ皮膚生検器を用いた耳血腫の治療法
- 犬の陳旧性ないし習慣性股関節脱臼に対する創外固定法の応用
- 顎関節強直および頬骨弓と下顎骨の癒着により開口困難を呈したネコの2例