Hemostatic effect of mouthwash containing tranexamic acid.
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概要
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The purpose of this study is to evaluate hemostatic effect of the mouthwash containing tranexamic acid (TR) which is known as a hemostatic and antiinflammatory drug.The hemostatic effect was studied by the modification of bleeding method with the peritoneum of a rat on the three kinds of test solution; mouthwash containing TR, blank solution (mouthwash without TR) and control (purified water).The following results were obtained;1) Hemostatic effect of the mouthwash containing TR could be evaluated by the modification of bleedind method with the peritoneum of a rat.2) It was recognized that hemostatic effect of the mouthwash containing TR was remarkably stronger than control at 30min. after administrations.3) The blank solution showed anti-hemostatic effect, which was presumably due to the effect of the ingredients contained in the solution, such as surface active agents, perfumes, antiseptic agents and so on.
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