Hemodynamic Changes under administration of Electrolyte Solution in Anesthetized Horses.

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Five horses were anesthetized with isoflurane for 2 hrs under the intravenous infusion with three different speed of lactated Ringer solution; no administration (control), 10 ml/kg/hr (10 mlgroup) and 40 ml/kg/hr (40 mlgroup) . Hemodynamic responses and hematocrit and serum protein values were measured at 30, 60, 90, 120 min after the beginning of anesthesia. Right atrial pressure and mean pulmonary pressure were unchanged in control, whereas increased gradually in infusion groups. At 60 and 120 min the value of right atrial pressure in 40 mlgroup was significant higher than those of other groups, and mean pulmonary arterial pressure in 40 mlgroup was significantly higher than that of control. Mean arterial pressure and systemic vascular resistance tended to increase, and cardiac output tended to decreased in all the groups in the course of time, however there were no significant differences between the groups in these parameters. Hematocrit and serum total protein levels decreased in infusion groups in the course of time, and those in 40 mlgroup were significantly lower than that of control at 60 to 120 min. At the end of anesthesia, three horses of 40 mlgroup revealed severe edema on their faces. Infusion of lactated Ringer solution was considered as not effective in maintaining blood pressure in anesthetized horse and administration of 40 ml/kg/hr lactated Ringer solution may not be safe.
獣医麻酔外科学会の論文