Correlation of the expression of intercellular adhesion molecule with the prognosis in primary oral squamous cell carcinoma.
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概要
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We carried out immunohistochemical investigations on the relationship of E-cadherin and α-catenin expression with the prognosis of patients with primary oral squamous cell carcinoma.We found that decreased (or lost) expression of E-cadherin and α-catenin closely correlated with cancer differentiation and mode of invasion. Furthermore, cancers with clinical lymph node metastasis displayed decreased (or lost) expression of both adhesion molecules.These findings suggest that investigations of the expression of the cadherin-catenin complex play an imoortant role in determining prognosis for patients with oral squamous cell carcinoma.
- 日本頭頸部癌学会の論文
日本頭頸部癌学会 | 論文
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