Clinical Studies on Non-epithelial Malignant Tumors of Head and Neck
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概要
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44 cases of non-epithelial malignant tumors of the head and neck without malignant lymphoma at Department of Otorhinolaryngology, School of Medicine, Keio University from 1962 to 1988 were studied. The age which ranged from 5 months old to 77 years old was widely distributed as compared with head and neck cancer. 25 patients were males and 19 paeients were females. Most of tumors arose from paranasal sinuses and nasal cavity (22 cases from maxillary sinus, 12 cases from nasal cavity). Rhabdomyosarcoma (9 cases), malignant melanoma (9 cases), osteosarcoma (6 cases), neurogenous sarcoma (6 cases) were fequently observed pathologically. In several cases, repeat biopsies were required because their pathological diagnosis was very difficult. Biopsy was done more than twice in the nearly half of cases. Therapeutic procedure for these tumors included surgery, radiotherapy, chemotherapy, immunotherapy and they were used in combination. But surgery was mainly done because they were often resistant to radiation and anticancer drug. We considered effective therapy for rhabdomyosarcoma, malignant melanoma, osteosarcoma, neurogenous sarcoma, which were frequently observed, as follows.rhabdomyosarcoma: surgery +chemotherapy+radiotherapymalignant melanoma: surgery+chemotherapy+radiotherapy+immunotherapyosteosarcoma: surgery+chemotherapy neurogenous sarcoma: surgeryThe prognosis was poor with a five-year survival rate of 32%. The recurrent rate was 43% and that of neurogenous sarcoma (83%) was especially high. Metastasis was most frequently to lung and lymphnode. The causes of death in most cases were intracranial invasion and lung metastasis.
- 日本頭頸部癌学会の論文
日本頭頸部癌学会 | 論文
- 口腔白板症に対する緑茶カテキンの治療効果に関する臨床的検討
- SUPERSELECTIVE ARTERIAL INFUSION AND CONCOMITANT RADIOTHERAPY FOR ADVANCED HEAD AND NECK CANCER
- MICROVASCULAR SURGERY IN HEAD AND NECK SURGERY
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