Clinical and Experimental Evaluations:on the Effects of Several Drugs against the Skin Connective Tissue
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概要
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A ten-years standing keloid was treated intralesionally with Lysozyme, Hyaluronidaseand Triamcinolone diacetate for 6 weeks and each effect was evaluated by thesoftening and planing of the lesions. Experimentally, fibroblasts originated from humanskin were cultivated in vitro in medium with the drugs respectively (Table 1 & 2), and examined morphologically under the microscopy.<BR>It was clear from the studies that Hyauronidase and Triamcinolone were effectivein the treatment of the keloid (Table 3) and inhibited the growth of fibroblast andcollagenogenesis in vitro (Table 4, 5., Phot. 5, 6 and 12-15), whearas Lysozyme didnot show apparent influence upon the tested materials.
- 日本皮膚科学会大阪地方会の論文
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