Two Cases of Necrobiosis Lipoidica.
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概要
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The first case was a 62-year-old woman who noticed sharp but irregular demarcated patches with erythema on both lower legs since the age of 57. As these lesions continued to increase in size, she visited our out-patient clinic on Feb.4, 1998. Skin biopsy revealed granulomatous change with disrupted collagen fibers in the dermis. She also had diabetes mellitus. The second case was a 60-year-old woman with progressive and erythematous, atrophic lesions on both lower legs. Biopsy specimen showed degenerative change in collagen fibers, surrounded by histiocytes and giant cells. She did not have diabetes mellitus.
- 日本皮膚科学会大阪地方会の論文
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