Papuloerythroderma(ofuji) Successfuly Treated with Oral PUVA Therapy: A Case Report.
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概要
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A 75-year old man had been suffering from pruritic eruptions for several years, which were resistant to corticosteroid therapy. Clinical findings were characterized by papules, plaques and pigmentation with cobble stone like appearance on the trunk and limbs sparing large folds. Blood eosinophils were evelated with the progress of the disease. Histological findings revealed acanthosis and spongiosis in the epidermis, and perivascular infiltration predominantly with lymphocytes in the upper dermis. No evidence was found for internal malignancy. PUVA therapy was commenced with the oral administration of 8-methoxypsoralen (30mg)and UVA irradiation (4J-6J/cm<SUP>2</SUP>). The eruptions disappeared almost completely after 33 treatments (177J/cm<SUP>2</SUP> UVA in total). Thereafter, UVB-phototherapy (100-200mJ/cm<SUP>2</SUP> per treatment) has been mainteined once or twice a week without recurrence.
- 日本皮膚科学会大阪地方会の論文
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