A Case of Contact Dermatitis due to BENTOS Eye Lotion Including Befunolol Hydrochloride.
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概要
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A 60-year-old male with contact dermatitis due to BENTOS<SUP>®</SUP> eye lotion is reported. Closed patch testing with BENTOS<SUP>®</SUP> (as is) was positive, while tests with the components of BENTOS<SUP>®</SUP>, befunolol hydrochloride 1%pet, befunolol hydrochloride 0.5%pet, befunolol hydrochloride 0.1%pet and benzalkonium chloride 1%pet, were also positive. However, a patch testing with 0.02% benzalkonium chloride (aq) obtained from the Japanese Society for Contact Dermatitis was negative. So he positive reaction to benzalkonium chloride 0.1%pet was thought to be an irritant reaction.<BR>In this case, there was no cross reaction among the 3 kinds of β-blocker in the eye lotion (BENTOS<SUP>®</SUP>, MIKERAN<SUP>®</SUP>, TIMOPTOL<SUP>®</SUP>).
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