A Case of Adult-onset Hypophosphatemic Osteomalacia Who was Misdiagnosed as Fibromyalgia Syndrome

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We report on a woman with hypophosphatemic osteomalacia (39 years old) who was misdiagnosed as having Fibromyalgia syndrome (FMS) . Her chief complaint was sciatica at her first visit to our institute. She had no neurological abnormalities, and no abnormal findings were detected by MRI or roentgenograms. Medication was not able to improve her symptoms.<BR>She had found out about FMS on the Internet, and believed herself that she was suffering from FMS. She visited another hospital by herself and was diagnosed as with FMS. She took some medicines, but her symptoms worsened. Two years later, she came to our hospital and complained that her height had become shorter by 5cm than it had been when she was younger. Her hematology was examined and showed hypophosphate and high ALP, indicating that she had osteomalacia. Her family history was unremarkable, and no tumor could be detected in her limbs by MRI. After vitamin D3 was taken, her back and leg pain decreased. A diagnosis of FMS should not be made without consideration of other metabolic diseases such as osteomalacia.
日本関節病学会の論文