Radiological and pathological studies on giant erosions of femoral heads and necks in rheumatoid hips.

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概要

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• Radiological and pathological studies were performed in 8 femoral heads and necks with giant erosions of 7 female patients with classical rheumatoid arthritis. Six hips of 5 cases received total hip replacements (THR) and the resected heads were examined pathologically. Radiologically, five of the giant erosions displayed a sclerotic wall on X-rays at the first visit, and there was no change in size by the THR thereafter. However, postoperatively a radiolucent area gradually appeared and progressed to the giant erosions. No further expansion occurred. All of the giant erosions arose from the lateral side of the femoral neck. The lesions were composed of fibrous granulation tissue of numerous mesenchymal cells and rich collagen fibers, and connected to the subsynovial tissues around the femoral neck. Pathologically, the giant erosions appeared to be an invasion of granulated tissue from proliferated subsynovial tissue at the lateral femoral neck where a thin cortex existed, although intra-articular pressure may have had some role in the invasive process.

• 日本関節病学会の論文

日本関節病学会 | 論文

• 関節リウマチ患者における手術と機能回復
• 低出力超音波刺激(LIPUS)および線維芽細胞増殖因子(FGF-2)の骨形成促進作用におけるヒアルロン酸(HA)の影響
• 変形性関節症に対するグルコサミン・コンドロイチンの有用性 (第36回[日本関節病]学会寄稿)
• 人工膝関節再置換術の経験--脛骨結節骨切り術の適応と合併症について
• RA頚椎病変に対する上位頚椎後方除圧固定術の治療成績と問題点

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