Radiotherapy for hepatocellular carcinoma: regarding solitary tumor on radiologic examinations.
スポンサーリンク
概要
- 論文の詳細を見る
OBJECTIVE: To evaluate the effect of radiotherapy (RT) on hepatocellular carcinoma (HCC) that appears as a solitary nodule on radiologic studies.<BR>MATERIALS AND METHODS: We irradiated 17 patients with solitary HCC lesions (25-150 mm in diameter) with approximately 60 Gy (range 50-70 Gy). Patients underwent dynamic CT and/or ultrasound imaging at 3-month intervals after treatment. Patients were classified based on lesion size, degree of cirrhosis (Child A, 6; Child B, 6; Child C, 5), and whether they had received other therapy such as transarterial chemoembolization (TACE). The responses were classified as complete, partial, no change, or progression.<BR>RESULTS: The median survival was 12.8 months for all 17 patients, with 1-, 2-, and 3-yea cumulative survival rates of 59%, 35%, 24%, respectively. Patients classified as Child A showed significantly longer survival than those classified as either Child B (p<0.04) or C (p<0.01). Four of the five Child C patients died of liver failure within 6 months after RT despite the absence of tumor recurrence. The initial tumor diameter, concurrent treatment with TACE, and radiation dose showed no significant effect on survival.<BR>CONCLUSION: Survival in patients with solitary HCC lesions appears to be affected mainly by the degree of liver dysfunction, and not the initial tumor diameter, radiation dose, or concurrent use of TACE.
- 一般社団法人 日本放射線腫瘍学会の論文
一般社団法人 日本放射線腫瘍学会 | 論文
- Radiotherapeutic Management of Isolated Loco-Regional Recurrence of Breast Cancer after Mastectomy.
- Radiation Therapy with or without Chemotherapy and Hyperthermia for Recurrent Rectal Cancer. Efficacy and Disadvantage of Combined Therapy.:EFFICACY AND DISADVANTAGE OF COMBINED THERAPY
- Thermoradiotherapy for Colorectal Carcinoma.
- タイトル無し
- EFFECTS OF INHOMOGENEITY CORRECTION ALGORITHMS ON MONITOR UNITS CALCULATION: ANALYSIS OF CLINICAL CASES OF LUNG CANCER