Mutagenicity of dusts from fire smoke
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概要
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While high volume sampling of air borne particulates for consecutive days, a fire of a house happened at 20 m distance from the sampling site. The sampler was surrounded with fire smoke for about 30 min.<BR>The concentration of total suspended particulates (TSP) was 0.10 mg/m<SUP>3</SUP> (24 hr average) in the before or after (ordinary) days, and the benzene extracts (tar) were 7.0-7.9 %, while the concentration of TSP in the fire day was 0.16 mg/m<SUP>3</SUP> and the tar was 10.6 %.<BR>Supposed that the increase of TSP in the fire day was due to the fire smoke, the concentration of TSP in fire time was estimated at 2.4 mg/m<SUP>3</SUP>, about 24 fold higher than in ordinary day and the tar in TSP at 17.7 %, 2.4 fold higher than in ordinary day. These estimations suggested that components of TSP in the fire time was rather different from those in ordinary days.<BR>Tar of the fire day, half of which originated from the fire smoke, was as mutagenic as those of ordinary days toward TA98 and TA 100 and showed linear dose dependency under 200μg/plate. The mutagenic activity was enhanced by S9 mix. At 400μg/plate, however, the increase of revertant colonies with the tar of the fire day was less than that with the tars of ordinary days in the presence of S9 mix or not. This effect did not seem to be due to toxicity of the tar.<BR>Inducibility of SCE of these tars was compared at 2 doses, 40μg/ml and 80μg/ml. SCEs were induced dosedependently by all the tars and statistically significant differences were not found among their SCE frequencies.<BR>Although mutagenic and SCE inducible activities per tar weight were similar in the fire day and ordinary days, those activities per air volume of the fire day were much higher, the former 30-90 fold and the latter 60 fold, than in ordinary days.
- 社団法人 大気環境学会の論文
社団法人 大気環境学会 | 論文
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