ASSOCIATION OF DENGUE VIRUS TYPE-SPECIFIC IGG ON PLATELETS IS SPECIFIC FOR THE ACUTE PHASE IN AN IMPORTED JAPANESE PATIENT WITH SECONDARY DENGUE 2 VIRUS INFECTION
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概要
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The mechanism of thrombocytopenia in dengue virus infection remains unknown. We report herein an imported case of a 21-year-old male Japanese with dengue fever caused by secondary dengue 2 virus infection. The thrombocytopenia detected around the day of defervescence was associated with an increased level of platelet-associated IgG (PAIgG). The eluate from the platelets during the acute phase of this case contained an increased activity of anti-dengue virus 2 IgG, while the eluate from platelets during the convalescent phase contained a low level of anti-dengue 2 IgG. These findings suggest the transient formation of PAIgG involving anti-dengue 2 virus IgG during the acute phase of secondary dengue 2 virus infection.
- 日本熱帯医学会の論文
日本熱帯医学会 | 論文
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