In vitro Effects of Decoction from Five Species of Chinese Plants against Trichomonas vaginalis.
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概要
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<I>In vitro</I> effects of extracts from the 5 species of Chinese herbal medicine against Trichomonas vaginalis, one of the most important protozoal diseases in China, were investigated. It was demonstrated that the extracts from <I>Artemisia annua, Phellodendron amurense</I> and <I>Pulsatilla chinensis</I> were highly effective against the protozoa at 1 to 5 hr after the start of the exposure to the drugs. The extract from <I>Cnidium monnieri</I> was much less effective and that from <I>Sophora flavescens</I> showed no activity even afterthe exposure for 5 hr. After this screening for excluding non-effective drugs, the parasites were exposed to all of the drugs except the extract from <I>S. flavescens</I>, the negative one in the above test, for 5 days at the drug concentrations lower than those above. The extracts from <I>A. annua</I> and <I>P. chinensis</I> were highly effective, immobilizing the parasites completely 2 or 3 days after the start of the exposure and afterwards. Contrarily, those from <I>C. monnieri</I> and <I>P. amurense</I> were not so effective. The results obtained in the present studies were in favour of the prospect that further studies including those on side effects, would be worthy of being carried out for the establishment of the chemotherapy of <I>T. vaginalis</I> infection with the crude drugs from medicinal plants in China.
- 日本熱帯医学会の論文
日本熱帯医学会 | 論文
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