マラリア患者の血液所見,特に貧血について

概要

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Parasite count and hematological studies were made on 170 falciparum, 220 vivax and 23 ovale malaria patients to see whether hematological parameters differ in malaria infected by three different species of malaria parasites, P. falciparum (PI), P. vivax (P. v.) and P. ovale (P. o.) The mean and percentage of abnormal values of each parameter were analyzed statistically. The parasite count was significantly large in the order of P. f.>P. v.>P. o. The maximum parasite count of P. f. was 2, 138, 000 per μl of blood. The mean parasite count for the 3 species was 18, 200, 3, 240 and 350 perμl of blood. The red blood cells (rbc) and hemoglobin (Hb) decreased significantly in the same order and the minium rbc count was 0.98 milion per μl and the lowest Hb concentration was 3.2 g/dl in falciparum malaria. The mean r. b. c. count in P.f., P.v. and P.o. malaria was 3.50, 3.81, and 4.12 million perμl and the mean Hb concentration was 11.0, 12.4 and 13.6 g/d/, respectively. The changes, either increase or decrease, in white blood cells and the decrease of platelets were not significantly different in P. f., P. v. and P. o. malaria. Nine cases of falciparum malaria were given blood transfusion, and its lifesaving merits in severely anemic patients and demerits of NANB hepatitis were discussed. Early treatment, within 5 days of the onset of illness, with rapidly acting antimalarial drug was emphasized.
日本熱帯医学会の論文