Correlation between filarial antibody titre and adult-T-cell leukemia virus antibody titre in inhabitants of Goto Islands, Nagasaki Japan.

概要

論文の詳細を見る
Goto Islands belong to Nagasaki Prefecture, and bancroftian filariasis had been endemic in these subtropical islands. For about 20 years, we have carried out the eradication program of bancroftian filariasis in two villages, Nagate and Daiho Village of Goto Islands. The eradication program was planned mainly through control of vector mosquito in Nagate Village and through treatment of persons with drug in Daiho Village. As a result of this program, no new filaria infection was found recently in these areas.<BR>On the other hand, Goto Islands are known as endemic areas of adult-T-cell leukemia (ATL). In this time, we have carried out a seroepidemiological study, and found that the groups of persons with positive ATLA antibody had significantly higher filarial antibody titre than those of persons with negative ATLA antibody in Nagate and Daiho Village.<BR>Thirty-four persons who were recorded as microfilaria carriers about 10 years ago showed higher positive rate of ATLA antibody than that of the others in Nagate Village.<BR>These data suggested that the filarial antigen stimulation might act as a factor in ATLV infection and/or proliferation among inhabitants in the endemic areas of filariasis and ATL.
日本熱帯医学会の論文