Cytological studies on a case of skin Merkel cell carcinoma. Cytomorphological comparison with small round cell tumor.:cytomorphological comparison with small round cell tumor
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Light & electron microscopic and immunohistochemical studies were performed on smear and biopsy of skin Merkel cell carcinoma. Noticeable findings are EMA, keratin, NSE and Neurofilament immunohistochemically positive, and dense by electron microscope. Button-like findings in the cytoplasm by papanicolaou staining were immunohistochemically positive for neurofilament, and topologically consistent with intermediate filament of ultramicroscopic structure. These fi ndings are characteristic and serve for differential diagnosis from other small round cell tumors. But Merkel cell carcinoma lacking neurofilament resembles pulmonary small cell carcinoma both cytomorphologically and immunohistochemically. Diagnostic differences of them depend on electron microscopic examination.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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