Misjudgement of histologic typing in cytology of lung adenocarcinoma. Correlation with cellular subtypes.:Correlation with cellular subtypes
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Twenty-six resected cases of moderately and well differentiated lung adenocarcinoma, diagnosed cytologically as lung cancer pre-operatively, were classified into cellular subtypes based on light microscopic observation of H-E stained specimens of the resected tumors, to determine the correlation between cellular subtypes and agreement of histologic typing in cytology.<BR>There were seven cases of bronchial surface epithelial cell type, thirteen Clara cell type, six mixed cell type, and no other types. All cases of Clara cell type were judged to be adenocarcinoma. Three cases of bronchial surface epithelial cell type were judged to be adenocarcinoma, and the other four cases were judged to be squamous cell carcinoma. Five cases of mixed cell type were judged to be adenocarcinoma, and another one was judged to be large cell carcinoma.<BR>Misjudged cases were all judged by brushing cytology, and all cases judged by sputum cytology were judged to be adenocarcinoma. Stratified arrangement of spindle shaped cells and necrotic findings were found in brushing cytology of the bronchial surface epithelial cell type.<BR>Cellular subtypes should be considered in judging histologic typing in brushing cytology of lung adenocarcinoma.
- 特定非営利活動法人 日本臨床細胞学会の論文
特定非営利活動法人 日本臨床細胞学会 | 論文
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