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Photodynamic therapy (PDT) is a treatment modality that utilizes photosensitizer activated by laser light, having the advantage of selective destruction of malignant tumor cells. However, the conventional dye laser used for PDT, such as the excimer dye laser system, is too large and costly. We developed a diode laser device, which is small, lightweight and easy to use, for PDT in combination with porfimer sodium and estimated its efficacy in tumor models. As a result, necrosis to a depth of about 10mm was obtained. This novel laser device may help expand the clinical applications of PDT.
日本レーザー歯学会の論文