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Photodynamic therapy (PDT) has proved its efficacy in the treatment of the early stage cancers of the lung, the esophagus, the stomach and the uterine cervex, and the health insurance of Japan already accepted its use in those lesions. We think oral early stage cancers and other oral lesions are also good candidates for PDT and its clinical applications. This report provides two cases of oral leukoplakia and oral verrucous carcinoma treated by PDT, monitoring by fluorescence diagnostic apparatus. Verrucous carcinoma was follow-up for 2 months, and I did not recognize a relapse, and our result was partial response. Leukoplakia recognized survival of lesion in treatment area circumference. It was useful to apply FLP-700 lesion monitoring in PDT.
日本レーザー歯学会の論文