Clinical Significance of Serum Soluble Fas Antigen in Patients with Primary Lung Cancer.

概要

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Objective: We evaluated the clinical significance of serum soluble Fas antigen (sFas) in patients with untreated primary lung cancer. Methods: Forty-five cases of untreated primary lung cancer, including 22 squamous cell carcinomas, 17 adenocarcinomas, 6 small cell carcinomas and 15 healthy controls were studied. Serum samples were obtained. The sandwich method with an sFas kit reagent (MBL Company, Nagoya, Japan) was used. Results: Compared with healthy controls, the levels of serum sFas in all cases of lung cancer were increased significantly in each pathological type and in each stage of lung cancer. In stage IV, sFas was significantly higher than in all other stages. Conclusion: Serum sFas was increased in primary lung cancer. Its elevation may be related with the situation of carcinoma. In stage IV, sFas was significantly higher than other stags.
特定非営利活動法人日本肺癌学会の論文