A Case of Adenocarcinoma of the Lung Associated with Giant Emphysematous Bulla Treated with Simultaneous Cisplatin, 5-fluorouracil, and Hyperfractionated Thoracic Irradiation.
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A 48-year-old man was referred to us, of a mass shadow in the infected emphysematous bulla by chest CT scannings. Neither bronchofiberscopic examination nor CT-guided transcutaneous biopsy could yielded a definitive diagnosis. By surgical resection of the extrapleural tumor directly invading the chest wall, poorly differentiated adenocarcinoma was diagnosed. Three cycles of chemotherapy consisting of cisplatin (20mg/m<SUP>2</SUP>×5 days) and 5-fluorouracil (500mg/m<SUP>2</SUP>×5 days), and simultaneous hyperfractionated thoracic irradiation (70Gy in a total dose with 1.25Gy×2/day) were immediately started and the mass shadow markedly regressed. Lung cancer with a coexisting bulla is frequently advanced and considered to have poor prognosis. Chemoradiotherapy may be useful for the treatment of unresectable advanced cases.
- 特定非営利活動法人 日本肺癌学会の論文
特定非営利活動法人 日本肺癌学会 | 論文
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