Adenocarcinoma of the Lung with a 14-year Clinical History Before Operation.

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On annual chest X-ray screening for pulmonary tuberculosis revealed an abnormal shadow in the left upper lung field in 1978 and 1979 of a 57-year-old office worker. In 1979, he was examined by fiberoptic bronchoscopy and percutaneous needle aspiration cytology, but findings at that time did not indicate lung cancer. He was treated with antituberculosis drugs for 21 months. Thereafter he was screened for tuberculosis every year. The abnormal shadow gradually increased in size. Fiberoptic bronchoscopy was performed again in 1992, 14 years after the first detection of the shadow. Brushing cytology revealed adenocarcinoma. We reexamined the previous slides of brushing and aspiration cytology and found cancer cells similar to those detected in 1992. Left upper lobectomy was performed. Histologically, the tumor contained abundant mucus and consisted of two cmponents, tubular adenocarcinoma imitating the structure of the bronchial gland and papillary adenocarcinoma.
特定非営利活動法人日本肺癌学会の論文