Evaluation of Craniotomy for Brain Metastasis of Non-small Cell Lung Cancer.

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• The clinical features and prognostic factors of thirty patients who received operations for brain metastases of non-small cell lung cancer between 1978 and 1994 were reviewed.Nine patients were metachronously diagnosed to have brain metastases after operation for primary lung lesion (recurrence), and 21 patients were synchronously diagnosed to have a brain metastasis with primary lung cancer (IV).Operation for primary lung cancer was performed in twenty one patients.Our results revealed that relatively favorable prognostic factors were female sex, recurrence, adenocarcinoma, single metastasis, curative operation for primary lung cancer and radical operations for both primary and metastatic regions.Statistically significant differences in survival were found1) between adenocarcinoma and large cell carcinoma, 2) between cases with over two years between detection of brain metastasis and the operation for primary lung cancer and those detected within one year after operation, 3) between those found to have no involvement of mediastinal nodes and those with mediastinal involvement positive. But there was no difference with regard to whether the prior operation was for the primary lesion or for the metastatic.We conclude that the prognosis of lung cancer without mediastinal node involvement and with synchronous oneset of brain metastasis is good of a curative operation for the primary lung lesion and brain metastases have been or will be performed.

• 特定非営利活動法人 日本肺癌学会の論文

特定非営利活動法人 日本肺癌学会 | 論文

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