Immunohistochemical Study of Adhesion Molecules Expressed on Lung Carcinoma Cells: Its Association with Lymph Node Metastasis.
スポンサーリンク
概要
- 論文の詳細を見る
Adhesion molecules were investigated in 48 cases of lung cancer, using an immunohistochemical technique.CD44, VLAβ1 and ICAM-1 were expressed in tumor cells, but other 8 adhesion molecules were largely absent.Adhesion molecules were present on the cell surface.CD44 and VLAβ1 were detected in 33 (69%) cases, and ICAM-1 was detected in 20 (42%) cases.The analysis of immunochemical data revealed that the positive cases for ant-CD44 mAb and ant-VLAfil mAb were significantly associated with lymh node metastasis (CD44: p<0.002, VLAβ1: p<0.05).Positivefindings for more than two mAbs showed even greather significant association.Our findings suggest that several adhesion molecules involving CD44 and VLAβ1 play an important role in lymphatic metastasis.
- 特定非営利活動法人 日本肺癌学会の論文
特定非営利活動法人 日本肺癌学会 | 論文
- 診療科からみた新しいTNM病期分類（UICC-7）の問題点と課題?画像診断からみた問題点と課題?
- 新潟県における肺がんの解析
- 慢性血栓塞栓性肺高血圧症合併肺腺癌に対する左上葉切除術を施行した1例
- 肺がん検診における判定基準の改訂（2）：B，C，D判定に関して
- 片側性多発脳神経障害（Garcin症候群）を契機に発見され，化学療法により神経症状の改善を得た小細胞肺癌の1例