Prognosis in Primary, Resected Non-small Cell Carcinoma Cases with Intrapulmonary Metastasis.

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The objective was to evaluate the prognosis of primary non-small cell carcinoma cases in a total of 794cases resected during the past 10years, including 64cases with intrapulmonary metastasis (pm) and 730cases without intrapulmonic metastasis (control).<BR>The overall 5-year survival rates in the pm group was 25% and there were no significant differences in survival between adenocarcinoma and squamous cell carcinoma, or between cases of Ti, T2, T3 and T4 disease.However, the survival rates of cases with metastasis to primary lobe tended to be better than cases of ipsilateral metastasis to non-primary lobe (s).Furthermore, significant differences of survival curves were demonstrated between cases with NO and N2 diseases and between cases with solitary and multiple metastasis (both P<0.05, Cox-Mantel test).The survival rates of cases with intrapulmonary metastasis were reevaluated according to the classification proposed by the AJCC and no significant differences were demonstrated in T2NO, T3NO, T4NO, N1, N2 deseases between the pm group and control group without intrapulmonary metastasis, supporting the suitability of the AJCC stage criteria for intrapulmonary metastasis.
特定非営利活動法人日本肺癌学会の論文