Pathological Findings of Atypical Carcinoid Tumors of the Thymus.

概要

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The pathological findings of three cases of thymic carcinoid tumors (two primary and one recurrent tumors) were studied. The tumors showed classical histological findings of carcinoid tumor, and tumor cells in all cases had argyrophillic granules and showed positive immunoreactivity for chromogranin A and neuron specific enolase. However, nuclear pleomorphism and/or mitotic activities were partially identified in all of the cases, and therefore, the diagnosis of atypical carcinoid tumor was made. Two of the three cases had recurrence or metastasis. The fact that all cases we encountered in the thymus were atypical carcinoid tumor suggests a worse biological character than typical carcinoid tumor derived in the thymus.
特定非営利活動法人日本肺癌学会の論文