An Operated Case of Thymoma with Immunodeficiency(Good syndrome) associated with Bronchogenic Carcinoma.
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概要
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A mediastinal tumor shadow was pointed out on a mass screening chest x-ray in a 74-year-old male. His chest CT happened to show a lung tumor in the left lower lobe in addition to the mediastinal tumor. His peripheral lymphocyte subset revealed a markedly low ratio of OKT4 to OKT8 and a deficit of the T-cell population. Both the mediastinal tumor and the lung tumor were simultaneously resected through the median sternotomy with left anterior intercostal thoracotomy. Histological examination revealed a spindle cell type thymoma and a primary lung cancer (squamous cell carcinoma), respectively. There was no change in the ratio of OKT4/8, postoperatively. In this case, it was unclear whether the thymoma itself caused the immunodeficiency and development of the lung cancer as a result of the failure of immunosurveillance system.
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