A Case of Adenocarcinoma of the Lung Combined with Metastatic Pulmonary Osteosarcoma Originating from the Fibula in a 13-year-old Girl.

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A case of adenocarcinoma of the lung combined with pulmonary metastasis from osteosarcoma in a 13-year-old girl was presented. She had been treated for osteosarcoma of the right fibula and bilateral multiple pulmonary metastases.<BR>The CT scan of the chest on admission revealed five mass shadows in both lung fields. She underwent a marginal resection of the right fibula and was treated by five courses of chemotherapy using high dose methotrexate and six courses of cisplatin + caffeine. After the chemotherapy, four of the mass shadows disappeared, and only the one in the left lower lobe remained. Partial resection of the left lower lobe was performed under the diagnosis of metastatic pulmonary osteosarcoma which was resistant to the induction chemotherapy. Histopathologically, the tumor was diagnosed as a primary adenocarcinoma of the lung.<BR>A CT scan 4 months after the operation detected five mass shadows in both lung fields. On the second operation, five nodules in the bilateral lung were resected. Histopathologically, all of the nodules were diagnosed as pulmonary metastasis of osteosarcoma.
特定非営利活動法人日本肺癌学会の論文