Comparison of the Size of Non-metastatic and Metastatic Lymph nodes of Mediastinal Lymph Nodes in Cases of Non-small Cell Bronchogenic Carcinoma.
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The longest transverse diameter (LTD) and shortest transverse diameter (STD) of 3855 resected mediastinal lymph nodes (3695 non-metastatic and 160 metastatic) obtained from 206 patients with non-small cell bronchogenic carcinoma were measured. Node measurement was performed using microscopic HE specimens, after classification of the region according to the node mapping of the Japan Lung Cancer Society. For revising the sizes of these nodes measured by HE specimens, decreasing rates of LTD and STD were respectively obtained from the other 58 resected nodes in which the LTD and STD were compared immediately after resection and those after preparing HE specimens. Comparison with non-metastatic and metastatic nodes were perfomed based on the revised diameters. The difference in LTD and STD between non-metastatic nodes and metastatic nodes was statistically significant (p<0.001 for both). To obtain a guideline for diagnosis of non-rnatastatic from metastatic lymph nodes based on size, the regional maximum standards of the LTD and STD of non-metastatic nodes were calculated. The STD showed a smaller variation and appeared to be a more useful parameter than the LTD. A standard maximum for normal STD for nodes in each region of the mediastinum was proposed as follows: 12mm for nodes in #7; 10mm for nodes in #1, #3, #4, #5 and #8; 8 mm for nodes in other regions.<BR>The LTD and STD of metastatic nodes (n= 120) of adenocarcinomas were statistically shorter than those (n=33) of squamous cell carcinomas (LTD: p<0.01; STD: p<0.005). The LTD and STD of metastatic nodes (n=120) of adenocarcinomas were statistically longer than those (n=3695) of non-metastatic nodes (Both LTD and STD: p<0.001).
- 特定非営利活動法人 日本肺癌学会の論文
特定非営利活動法人 日本肺癌学会 | 論文
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