Relationship Between Operative Procedure and Prognosis of Patients with Interlobar Invading Lung Cancer Lesions.

概要

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A total of 65 patients who had interlobar invading lung cancer lesions underwent surgical resection. The 5-year survival rate of these cases was 42%. Of the 65 patients, the 52 patients who were treated with complete resection had a significantly higher survival rate than the 13 patients who underwent incomplete resection (52% vs. 0%).<BR>Of the 52 patients who were treated with complete resection, the 5-year survival rate of the 28 patients who underwent lobectomy of the invaded lobes (Group A) was significantly higher than that of the remaining 24 patients who underwent partial resection of such lobes (Group B) (74% vs. 27%). In particular, there was a significant difference between these two groups in adenocacinoma, in NO cases, and in N1 cases.<BR>Causes of death were compared between Group A and Group B according to nodal involvement. Almost all of the N2 cases in both groups died of distant metastasis. However, in N1 and NO cases, the recurrence rate in the ipsilateral hemithorax and the mortality of Group A were lower than those of Group B.<BR>To improve the survival rate of patients with interlober invading lung cancer lesions, bilobectomy or pneumonectomy should be performed. However, in patients 70 years of age or older, pneumonectomy is not recommended, since it did not improve the survival rate of such elderly patients.
特定非営利活動法人日本肺癌学会の論文