A Case Report of Primary Mediastinal Germ Cell Tumor Resected Following Combination Chemotherapy with Cisplatin, Etoposide, and Bleomycin.

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An 18-year-old male was admitted with a complaint of right chest pain. Chest X-ray revealed an anterior mediastinal tumor and multiple pulmonary tumors. The serum alpha-fetoprotein and human-chorionic gonadtropin were markedly elevated (AFP: 674.94ng/ml, HCG: 4364mIU/ml). No abnormality was found in the testis. He was diagnosed as having a primary mediastinal germ cell tumor with multiple pulmonary metastasis.<BR>After three courses of chemotherapy, which consisted of high-dose cisplatin, etoposide and bleomycin, the serum tumor markers became normalized. Following chemotherapy, the residual tumors were resected. The resected tumors consisted of immature teratoma and necrotic tissue. The patient is free of the disease at present.
特定非営利活動法人日本肺癌学会の論文