Study of second cancer among patients disease-free for 2 or more years after treatment of primary lung cancer.
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概要
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A study on second cancer was performed among 213 patients who wer disease-free for 2 or more years after the start of treatment for primary lung cancer by surgical resection (196 patients) or nonsurgical procedure (17 patients). Second primary cancers were observed in 11 patients, including 7 patients treated by surgical resection and 4 patients by nonsurgical treatment.<BR>The organ in which the second cancer developed was the lung in 8 patients and the stomach in 3 patients with the former representing an excessively high-risk organ after the first lung cancer.<BR>Histologically, the majority were squamous cell carcinoma for both primary and second (lung) cancers. All the patients were heavy smokers (cigarette index exceeding 400), and a correlation between cigarette smoking and second cancer was suggested.<BR>Most patients remained asymptomatic before detection of second cancer on periodical examination. This finding emphasizes the importance of regular checkups after treatment of lung cancer.
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