Postoperative 5-year disease-free rate in patients with small peripheral adenocarcinoma of the lung with respect to histopathological findings.

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The disease-free rate of 50 resected cases of peripheral small adenocarcinoma of the lung (tumor diameter, 2.0 cm or less) treated at 7 hospitals in Osaka from January 1977 to December 1981 was studied.<BR>The 5-year disease-free rate of the 33 cases in the nO group was 77.3%, while the rates for the n1 and n2 groups were markedly lower at 40.0% and 34.7%, respectively. The combined 5-year disease-free rate for all 50 cases was 63.8%. Lymph node metastasis was found in approximately one third of all cases, and n2 cases were more than twice as common as n1 cases, with n2 cases making up one fourth of the total number of cases.<BR>The disease-free rate was also found to be markedly lower in T2 or T3 groups and in parietal p2 or p3 groups. The histopathological findings showed a markedly lower disease-free rate in cases which had a large number of mitotic figures and in cases in which there was no lymphocytic infiltration.<BR>he 5-year disease-free rate for 12 cases in which the tumor diameter was 1.5 cm or smaller was 55.6%, showing no significant difference from the rate for cases with a tumor diameter of 1.6 -2.0 cm.
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