Statistical Analysis Concerning Routes of Dissemination of Small-cell and Large-cell Carcinoma of the Lung Based on the Autopsy Records

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This paper described statistical analysis concerning routes of dissemination of smallcell and large-cell carcinoma of the lung based on 576 autopsy records. The analysis of average number of cases with metastasis at minor metastatic sites were carried out using occurrence or non-occurrence of major metastatic sites (lung and liver) as 2 X 2 factorial design.<BR>The results were as follows;<BR>1) The dissemination of large-cell carcinoma of the lung was influenced mainly by the presence of metastasis in the liver, whereas that of small-cell carcinoma was influenced by the presence of metastasis in the liver and the lung.<BR>2) The frequencies of metastasis to the lung, intestines, kidney and spleen in large-cell carcinomas were significantly higher than those in small-cell carcinomas.<BR>3) The frequencies of metastasis to the pancreas and bones in the small-cell carcinomas were significantly higher than those in the large-cell carcinomas.
特定非営利活動法人日本肺癌学会の論文