Giant cell carcinoma of the lung A cytological evaluation

スポンサーリンク

概要

• 論文の詳細を見る

• In 1958, Nash and Stout called attention to a type of primary lung cancer comprised principally of giant cells and variable focuses of anaplastic frequently mesenchymal-like components resembling rhabdomyosarcoma or osteosarcoma.<BR>Giant cell carcinoma of the lung occurred at a younger age, exhibited widespread metastases, and pursed a more rapid, fulminant course than histological variants. Its lower resectability rate compared to other lung carcinomas.<BR>We studied materials before radiation and chemotherapy in five cases of giant cell carcinoma of the lung obtained by bronchoscopic brushing method and transthoracic aspiration. These materials were informative for study of fresh cancer cells.<BR>Chest x-ray findings in all cases a nodular shadow.<BR>Morphological features were studied with stain methods such as Pap., Giemsa, PAS, Mucicarmin, and Alcianblue reaction.<BR>Multinucleated and uninucleated bizzarre giant cells showed to phagocytize neutrophils, and debris and uneven dispersed distribution or a pooly cohesive groups but never in tight clusters. Occasionally cancer cells were found in necrotic substances. The cancer cells were round or smooth but showed lobulation, budding, indentation and constriction, and chromatin was coarsely or fine and rich. The nucleoli were round and small.<BR>In differential diagnosis, we studied on similarity and difference with epidermoid carcinoma, choriocarcinoma, rhabdomyosacoma, osteosarcoma, Langhans's giant cell and histiocyte.

• 特定非営利活動法人 日本肺癌学会の論文

特定非営利活動法人 日本肺癌学会 | 論文

• 診療科からみた新しいTNM病期分類（UICC-7）の問題点と課題?画像診断からみた問題点と課題?
• 新潟県における肺がんの解析
• 慢性血栓塞栓性肺高血圧症合併肺腺癌に対する左上葉切除術を施行した1例
• 肺がん検診における判定基準の改訂（2）：B，C，D判定に関して
• 片側性多発脳神経障害（Garcin症候群）を契機に発見され，化学療法により神経症状の改善を得た小細胞肺癌の1例

もっと見る

スポンサーリンク