Required sample sizes in clinical trials for lung cancer treatment results that the survival-time patterns of patients have lognormality

概要

論文の詳細を見る
In this paper the author tried to calculate sample sizes for clinical trials in lung cancer treatment results that the survival-time patterns of patients have lognormality using the Owen's noncentral t-distribution and given following tables.<BR>The table la and lb are given the relation between the expected difference Δμ in logmean and the required sample sizes that should be included in each group of a clinical trial in lung cancer treatment results in oder to have a 90% (β=0.90), 70% (β=0.70) and 50% (β=0.50) probability detecting significant difference (!α=0.05, α=0.01) in results and covered any value of the difference ranging from 0.03 to 0.30 and any value of ranging from 0.30 to 0.50.
特定非営利活動法人日本肺癌学会の論文