Studies on Radiotherapy of Primary Lung Cancer by CO-60 delivering 600R Twice a Week
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We treated 139 patients with primary lung cancers by CO-60 from 1964 to 1971.The size of single dose was 600R twice a week and therefore 1200R in a week-dose.The total of dosage used was from 6000R to 8400R over a period from 5 to 7 weeks in most cases.<BR>As control, 148 patients treated by daily dose of 200R six times per week were compared with this trial.<BR>The consequence of our studies was evaluated by crude survival rate, median survival months and tumor regression rate.The procedure of 600R twice a week has a better therapeutic effect than control.<BR>As to side effects we checked local and general side effects.In regard to skin reactions, erythema and dry reactions occured in most cases, but moist reactions occured in only 2 cases.<BR>Pulmonary pneumonitis has been seen in about 60% of cases between the end of and 3 months after the treatment.In the cases of delivering 8000R or more, pneumonitis occured in almost all the cases within 2 months from the beginning of treatment.But, administration of medicines eliminated severe symptoms due to pneumonitis or fibrosis.<BR>White cells were examined once a week in all cases, 3000/mm3 of white cells were regarded as a minimal for further irradiation.White cell counts of more than 4000 were 54.9%, 4000 to 3000 40.7%, and below 3000, 4.4% respectively.<BR>Thrombocytes below 100, 000/mm3 were seen only in a few, and red cells showed no appreciable change.<BR>Tumors were regressed approximateoy the same degree by both types of treatments without conspicuous side effects.<BR>In addition, in our procedure anti-tumor drugs and hyperbaric oxygen therapy can be utilized relatively easily during unirradiated time.
- 特定非営利活動法人 日本肺癌学会の論文
特定非営利活動法人 日本肺癌学会 | 論文
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