Electrophysiological studies of the cochlea of the guinea pigs with experimental renal failure.
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概要
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In order to investigate the relationship between renal failure and hearing loss, we made the guinea pigs with renal failure which was experimentally induced and examined the cochlear potentials (AP, CM and EP).As the renal damage was higher, the amplitude of AP and CM were decreased and the latency of AP was prolonged. But EP was within normal range. It was thought that the sensory cells of the cochlea was responsible for hearing loss of the guinea pigs with renal failure. No pathological findings of the cochlea was found under a light microscope, and it was suggested that the etiology of hearing loss was mainly metabolic disturbances such as uremic toxicities, electrolyte imbalance and endocrine abnormalities.
- 日本聴覚医学会の論文
日本聴覚医学会 | 論文
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